http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102185428-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-02 |
| filingDate | 2020-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102185428-B1 |
| titleOfInvention | Expression vectors for optimal expression of mutated Upc2p and method for overproducing sterol precursors using the same |
| abstract | The present invention relates to a vector for optimizing expression of a mutant transcriptional regulator Upc2p and a method for overproduction of a sterol precursor using the same, and in detail, feedback regulation by optimizing the expression of a mutant transcriptional regulator (Upc2p) with a reduced affinity for ergosterol This alleviates the ergosterol biosynthetic pathway as a whole to produce a recombinant yeast with improved biosynthesis of sterol precursors such as epoxy squalene and squalene and ginsenoside precursors such as dammarenediol. The mutant UPC2 expression cassette developed in the present invention and the replacement cassette using the CRISPR system and the recombinant yeast strains produced using the same can be utilized for the production of ginsenoside or UDCA precursor mass biosynthetic recombinant yeast through additional metabolic engineering. . |
| priorityDate | 2020-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 684.