http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102175170-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-324 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-912 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-45 |
| filingDate | 2019-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102175170-B1 |
| titleOfInvention | Composition for treating hepatitis B comprising inhibitor of HBV enhancer, ACK1 |
| abstract | The present invention relates to a composition for the treatment of hepatitis B comprising an HBV (hepatitis B virus) enhancer (enhancer) inhibitor ACK1 (activated cdc42-associated kinase 1). Specifically, in the cell line into which the ACK1 gene produced in the present invention and the hepatitis B virus (HBV) replicon were introduced, the HBV replication was inhibited according to the inhibition of the transcription process of HBV according to the expression of ACK1 and accordingly Antigen secretion inhibitory effect appeared, and the effect was stronger in the cell line stably expressing ACK1. In addition, it was confirmed that the inhibitory effect of ACK1 on HBV enhancer activity is due to the regulation of expression of a transcription factor that binds to and regulates the activity of the HBV enhancer, the ACK1 protein of the present invention, a polynucleotide encoding it, or a vector containing the polynucleotide A composition containing as an active ingredient can be usefully used as a composition for preventing, treating or improving hepatitis B. |
| priorityDate | 2019-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 776.