http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102170266-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate | 2013-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102170266-B1 |
| titleOfInvention | GRAFTED CONJUGATES OF POLYSACCHARIDES AND siRNAs, siRNA DELIVERY SYSTEM COMPRISING THE SAME AND PREPARING METHOD THEREOF |
| abstract | The present invention relates to a polysaccharide polymer derivative grafted with siRNA, a gene delivery system including the same, and a method for preparing the same.The siRNA delivery system according to the present invention has high dispersion stability because the polysaccharide polymer is located on the surface of the delivery system. Since it can be stably present in the body for a long time without clumping, it can effectively inhibit the protein expression of the target gene. After entering the body, it is possible to easily restore the original structure of the siRNA having biological activity in the cell, and also on the surface. By introducing and using functional molecules suitable for target treatment according to various target diseases by using the functional groups of the located polysaccharide polymer, the therapeutic effect can be remarkably increased, so it can be used in various gene therapy fields using siRNA. |
| priorityDate | 2013-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.