http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102161720-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L29-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-10 |
filingDate | 2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102161720-B1 |
titleOfInvention | Composition for preventing or treating non small cell lung cancer harboring the EGFR mutations |
abstract | The present invention relates to a composition for preventing, improving, or treating EGFR-mutant non-small cell lung cancer, comprising a JNK (c-Jun N-terminal kinase) activator as an active ingredient. The composition for preventing, improving or treating EGFR-mutant non-small cell lung cancer of the present invention is useful for preventing, improving or treating non-small cell lung cancer by significantly reducing the EGFR level of EGFR-mutant non-small cell lung cancer cells and causing apoptosis. Can be used. In particular, it is possible to effectively treat and prevent non-small cell lung cancer in which gefitinib or erlotinib is not effective. In addition, the composition for inhibiting the resistance of non-small cell lung cancer to the EGFR tyrosine kinase inhibitor of the present invention effectively overcomes the resistance to the EGFR tyrosine kinase inhibitor. |
priorityDate | 2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 204.