http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102159332-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-76 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate | 2018-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102159332-B1 |
| titleOfInvention | Composition for inducing selective apoptosis undifferentiated pluripotent stem cells comprising magnolia extracts and the Method for inducing selective apoptosis using the same |
| abstract | The present invention relates to a composition for inducing selective apoptosis of undifferentiated pluripotent stem cells comprising a Hubak extract as an active ingredient, and specifically, a composition for inducing selective apoptosis of undifferentiated pluripotent stem cells containing Hubak extract as an active ingredient , A composition for selective removal of undifferentiated pluripotent stem cells comprising the extract as an active ingredient, (a) preparing a cell sample including undifferentiated pluripotent stem cells and differentiated cells; And (b) selectively removing undifferentiated pluripotent stem cells by treating the cell sample with a fugitive extract; comprising, a method for removing undifferentiated pluripotent stem cells, and in which undifferentiated pluripotent stem cells are removed by the method. It relates to a cell composition. In a situation where the undifferentiated stem cells remaining in the process of differentiation of pluripotent stem cells have a problem that can form teratoma (teratoma) when transplanted as a cell therapy agent, the composition comprising the extract of the present invention can differentiate pluripotent stem cells. In the process, since only stem cells remaining in an undifferentiated state can be effectively removed, it can be used to develop a safe stem cell therapeutic agent. |
| priorityDate | 2018-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.