http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102152077-B1

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filingDate 2019-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ef3dde2d6c2608792087ca8ea55aff5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e86506e24fe26d4f3466ae461f4536a4
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publicationDate 2020-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102152077-B1
titleOfInvention Papain enzyme treated silkworm segment extracts having excellent skin anti-inflammatory effect and use thereof
abstract The present invention relates to a cocoon-derived papain enzyme decomposition product having excellent skin inflammation improving activity and a use thereof, and in particular, the present invention relates to a method for preparing a papain enzyme digestion product of a cocoon having an activity to inhibit or improve skin inflammation, the method It relates to a cosmetic composition for improving skin inflammation, comprising a papain enzyme decomposition product for the ultrasonic extract of the cocoon prepared as an active ingredient, a health functional food, and a pharmaceutical composition for preventing or treating skin inflammation. The papain enzyme decomposition product of the cocoon according to the present invention has excellent inhibitory activity of COX-2 and PGE2, which are factors causing skin inflammation, and at the same time can inhibit phosphorylation of extracellular-signal-regulated kinase (ERK), It can be usefully used in the manufacture of cosmetics, medicines and health functional foods for the prevention, improvement or treatment of skin inflammation.
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ7A742
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP06757
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP48814
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP23991
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP48815
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP08317
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO22585
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP42327
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID469616
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP80572
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP42328
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID280828
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP10537
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP0DJA2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP79341
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP10538
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP07159
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP07160
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4UYK8
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID405770
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ4R1E8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP48977
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA0A803JUX3
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID395196
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP07161
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ96533
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP10127
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID403974
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB6CKP4
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP07162
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCF8DVL8
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID23665730
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100136689
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID14982
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP07246
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9WVG1
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID433323297
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5280360
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP79162
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCH9A0J9
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP79182
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP41680
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP79255
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ00669
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID55670
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9MZR1
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP41681
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID280826
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ00670
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP41683
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID447791568
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ00671
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ75ZX4
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP41687
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ865W7
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ6GJ63
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ00672
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP10145
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP41693
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ7U1B9
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP23361
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ2YSX0
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP41747
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ2R8Z5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8VZ49
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00333
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ865X6
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID443460
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6918840
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00334
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ865X8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8WNR2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ0KDL6
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24498
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID448814769
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP14940
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP43067
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP26889
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP23237
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5AR48
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA3FBE9
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP26892
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100136024
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP23277
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP55005
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB4M8Y0
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP26893
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP14674
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP41324
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9VV43
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ7TQD2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP23278
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID281251
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP26894
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID396451
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP14675
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP9WQC0
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP28332
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP54202
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP9WQC1
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO97959
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ95181
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO94811
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9GN94
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP9WQC2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00329
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ0ITW7
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP9WQC3
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5XI95
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00330
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCE1ACQ9
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ2G0G1
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP9WQC6
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00331
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID14798
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP9WQC7
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8LEB2

Total number of triples: 427.