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publicationDate 2020-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102150825-B1
titleOfInvention Novel sglt-2 inhibitors cocrystal
abstract As a result of trying to improve the low stability and water solubility, which is a problem of empagliflozin, an empagliflozin/citric acid co-crystal with increased stability and water solubility by more than 60 times was developed. This empagliflozin/citric acid co-crystal is a new solid form that overcomes the stability and water solubility of the known empagliflozin crystal form, and is very useful as an optimal SGLT-2 inhibitory drug that can maximize its use as a drug. Do.
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