http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102145290-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-322 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate | 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102145290-B1 |
| titleOfInvention | Composition for preventing or treating ischemic brain disease comprising DAPK1 or Pin1 inhibitor |
| abstract | The present invention relates to a pharmaceutical composition for the prevention or treatment of ischemic brain diseases comprising an inhibitor of DAPK1 (Death-associated protein kinase 1) or Pin1 (peptidylprolyl cis/trans isomerase 1) as an active ingredient. When the treatment of DAPK1 or Pin1 of the present invention alone or in combination, it induces neuronal protection and neuroplasticity, reduces the expression of apoptosis-inducing activator, and reduces the activity of DAPK1 or Pin1-mediated apoptosis mechanism. By confirming that it effectively treats and prevents ischemic brain disease, it can be usefully used in the related pharmaceutical field. |
| priorityDate | 2017-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 218.