| abstract |
The present invention is a liposomal herbal ingredient for treating or alleviating joint pain by allowing it to penetrate into the skin by a transdermal drug delivery component while eluting a herbal drug extract having an effect of helping to treat or relieve joint pain. It relates to a transdermal drug delivery patch composition and a patch manufacturing method using the composition. The transdermal drug delivery patch composition for the treatment of joint pain of the present invention comprises a herbal extract consisting of peppermint leaves, Ecklonia cava, cinnamon sticks and gasiogapi, a transdermal drug delivery component, and a hydrogel that changes from a gel state to a sol state in response to skin temperature. The composition is mixed, but the herbal medicine extract is composed of a mixture of peppermint leaves, Ecklonia cava, cinnamon sticks and gasiogapi at a weight ratio of 1 to 2: 1 to 2: 1: 1 to 2, respectively, and the herbal extracts are phospholipids and 0.2 to 1 : In the state of being mixed at a weight ratio of 1, sonication is performed for 3 to 5 seconds at 1 to 3 seconds intervals for 2 to 30 minutes, so that the herbal medicine extract component is divided into nanoparticles, surrounded by phospholipids, and is liposomed, and herbal extracts 5 to 15 Wt% and 45 to 55 wt% of polyacrylic acid as a transdermal drug delivery component, 0.4 to 2 wt% of agar as a hydrogel material, 0.01 to 0.5 wt% of sodium hydroxide, 5 to 15 wt% of glycerin, 3 to of methylpropanediol 7% by weight, sodium polyacrylate 0.2-1% by weight, aluminum glycinate 0.05-0.5% by weight, and the rest are mixed with purified water. |