http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102137786-B1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1682
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
filingDate 2018-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102137786-B1
titleOfInvention Preparation method of microspheres for injectables
abstract The present invention relates to a method of manufacturing microspheres for injection, a specific method of manufacturing is a) by dissolving by adding a biodegradable polymer to an organic solvent, and dissolving or dispersing by adding a drug to a solution in which the biodegradable polymer is dissolved. Forming a solution; b) dissolving the emulsifier in water to form a second solution; c) mixing the first solution and the second solution to form a biodegradable polymer droplet containing a drug; d) forming a biodegradable polymer microsphere comprising a drug; And e) filtering, washing and drying the microspheres to remove the emulsifier. In detail, the emulsifier is characterized in that the polyvinylpyrrolidone-polyvinyl acetate copolymer (poly(vinyl pyrrolidone-co-vinyl acetate), PVP/VAc) represented by the following formula (I). Formula I In the formula (I), n is the mole number of polyvinylpyrrolidone, and m is the mole number of polyvinyl acetate.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022270956-A1
priorityDate 2018-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 45.