http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102137786-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
filingDate | 2018-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102137786-B1 |
titleOfInvention | Preparation method of microspheres for injectables |
abstract | The present invention relates to a method of manufacturing microspheres for injection, a specific method of manufacturing is a) by dissolving by adding a biodegradable polymer to an organic solvent, and dissolving or dispersing by adding a drug to a solution in which the biodegradable polymer is dissolved. Forming a solution; b) dissolving the emulsifier in water to form a second solution; c) mixing the first solution and the second solution to form a biodegradable polymer droplet containing a drug; d) forming a biodegradable polymer microsphere comprising a drug; And e) filtering, washing and drying the microspheres to remove the emulsifier. In detail, the emulsifier is characterized in that the polyvinylpyrrolidone-polyvinyl acetate copolymer (poly(vinyl pyrrolidone-co-vinyl acetate), PVP/VAc) represented by the following formula (I). Formula I In the formula (I), n is the mole number of polyvinylpyrrolidone, and m is the mole number of polyvinyl acetate. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022270956-A1 |
priorityDate | 2018-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.