http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102132221-B1

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filingDate 2019-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_145182de649528b5bfdb386f357f963d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fa75f7112ac13c682a78c1a8660f20a
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publicationDate 2020-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102132221-B1
titleOfInvention Regulation mechanism of allergic reaction by miR-154-5p, and use thereof
abstract The present invention relates to a mechanism for regulating an allergic reaction by miR-154-5p and its use, specifically measuring the expression level of miR-154-5p from a sample in order to provide information necessary for diagnosis of an allergic disease of a test subject Method, a pharmaceutical composition for preventing or treating allergic diseases containing an active inhibitor of miR-154-5p as an active ingredient, and a screening method for treating allergic diseases using a mechanism for controlling allergic reactions by miR-154-5p. According to the present invention, it is possible to effectively provide information necessary for the diagnosis of allergic diseases through a method of measuring the expression level of miR-154-5p, and the pharmaceutical composition according to the present invention containing an active inhibitor of miR-154-5p Using can effectively prevent or treat allergic diseases. In addition, it is expected that a method for screening a substance that reduces the expression of miR-154-5p can effectively search for a treatment for allergic diseases, and is expected to greatly contribute to the development of a new and more effective treatment for allergic diseases.
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