http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102124614-B1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-922 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2018-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102124614-B1 |
titleOfInvention | Composition for Diagnosing Antibacterial Susceptibility Comprising an Agent for Detecting Nuclease in Microorganism and Uses Thereof |
abstract | The present invention relates to an antimicrobial susceptibility diagnostic composition comprising an agent that detects a microbial nuclease and uses thereof, wherein the agent to detect the microbial nuclease is a FRET-DNA probe, and the FRET-DNA probe-based AST ( F-AST) F-AST probes when antibiotic-sensitive susceptibility tests of certain microorganisms are performed according to the method, as a result of antibiotic-induced bacterial lysis, bacterial cells are lysed and total protein, including nucleases, is liberated from the lysate Is cut by a nuclease, and a quencher and a fluorophore are separated at a distance, so that a significant increase in fluorescence signal is realized, so that the antimicrobial susceptibility of microorganisms can be accurately and quickly confirmed. Therefore, the F-AST system of the present invention is not only easy to implement, quick and economical, but also designed to be read with a microtiter plate reader, so that existing technologies can be easily utilized to provide the basis for clinical treatment. do. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220057424-A |
priorityDate | 2018-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 191.