http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102117216-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-25 |
filingDate | 2012-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102117216-B1 |
titleOfInvention | Novel gh-rh analogs with potent agonistic effects |
abstract | Synthetic peptides having the following sequence and pharmaceutically acceptable salts thereof: [RrAļ¼¼A 2 , A 6 , A 8 , A 11 , A 12 , A 15 , A 20 , A 21 , A 22 , Nle 27 , A 28 , A 29 , A 30 ] hGH-RH (1-30) -R 2 (SEQ ID NO: 1). [here, R 1 is Ac, Tfa, or absent, A 1 is Tyr, Dat, or N-Me-Tyr, A 2 is Ala, D-Ala, Abu, or D-Abu, A 6 is Phe or Fpa5, A 8 is Asn, Ala, Gin, Thr, or N-Me-Ala, A 11 is Arg, His, or Har, A 12 is Orn, or Lys(Me) 2 , A 15 is Abu, or Ala, A 20 is Arg, His, or Har, A 21 is Orn, or Lys(Me) 2 , A 22 is Leu, or Orn, A 28 is Ser, or Asp, A 29 is Arg, Har, Agm, D-Arg, or D-Har, A 30 is Arg, Agm, Ada, Amc, Aha, Apa, Har, D-Arg, D-Har, Gab, Gin, D-GIn, Gin-Gab, D-Gln-Gab, or absent. R 2 is -NH 2, -OH, -NHR 2, -N (R 2) 2, or -OR 2, wherein, R 2 is C 1 -12 alkyl, C 2 -12 alkenyl, or C 2 - 12 is one of alkynyl, However, when A 29 is Agm, A 30 and R 2 are absent, and A 1 is only N-Me-Tyr.] |
priorityDate | 2011-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 450.