http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102107272-B1

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0211
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04
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filingDate 2014-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102107272-B1
titleOfInvention Enhanced regio-selectivity in glycol acylation
abstract Methods of acid-catalyzed acylation of isohexides have been described. The method involves the reaction of isohexide and excess carboxylic acid in the presence of a Lewis acid or Bronsted acid catalyst. One or more Lewis acids and / or Bronsted acids can achieve high conversion rates of isohexide to the corresponding mono and diesters with much higher regioselectivity of exo -OH than the endo -OH of isohexide in the product. have. Certain catalytic acid species include zirconium chloride (ZrCl 4 ) and phosphonic acid (H 3 PO 3 ), which exhibit ratios of exo : endo reactivity of about 5: 1 and 4: 1, respectively.
priorityDate 2013-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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