http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102100360-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5161 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate | 2018-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102100360-B1 |
| titleOfInvention | A photothermal nanocomplex comprising photothermal nanoparticle, anticancer drug and conjugate of hyaluronic acid and substrate peptide of cathepsin B |
| abstract | The present invention is photothermal nanoparticles; Anticancer drugs; And a conjugate of a substrate peptide of hyaluronic acid and cathepsin B, wherein the conjugate of a substrate peptide of hyaluronic acid and cathepsin B relates to a photothermal nanocomposite bound to the surface of the photothermal nanoparticle, In the photothermal nanocomposite according to the present invention, the conjugate of the substrate peptide of hyaluronic acid and cathepsin B is bound to the surface of the photothermal nanoparticles, thereby targeting cancer cells by binding to the hyaluronic acid receptor CD44 expressed on the surface of the cancer cell. , It can be released into the lysosome in cancer cells and release the anti-cancer agent while the conjugate is cut by cathepsin B present in the lysosome. In addition, the photothermal nanocomposite of the present invention exhibits an excellent cancer treatment effect since it simultaneously has a photothermal treatment effect by photothermal nanoparticles and a chemotherapy effect by an anticancer agent when irradiated with near infrared rays. |
| priorityDate | 2018-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.