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filingDate 2018-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102094338-B1
titleOfInvention the composition comprising the extract of Veronicastrum sibiricum L. Pennell as an active ingredient for preventing or treating inflammation, allergy and asthma and the use there of
abstract The present invention relates to a composition for preventing or treating inflammation, allergies and asthma, which contains an extract of cold vinegar (Veronicastrum sibiricum L. Pennell; Veronicastrum: cold vinegar) as an active ingredient. Cold vinegar extract according to the present invention is a leukotriene (leukotriene) generation inhibitory ability evaluation test (Experimental Example 1); Experiment on the effect on total cell count in total bronchoalveolar lavage (BAL) using Balb / c male mouse (Experimental Example 2); Experimental effect on the number of neutrophil cells compared to the total number of cells in total bronchoalveolar lavage (BAL) (Experimental Example 3); Experiment on the effect on the number of Neutrophil + / Gr-1 + absolute cells in bronchoalveolar lavage fluid (Experimental Example 4); Experiment on the effect on the number of CD11b + / Gr-1 + absolute cells in lung cells (Experimental Example 5); Experiment on the effect on the number of CD4 + / CD3 + absolute cells in lung cells (Experimental Example 6); Effect of macrophage + / CD11b + absolute cells in lung cells (Experimental Example 7); Experiment on the effect of bronchoalveolar lavage fluid (BAL fluid) on inflammatory factor expression level (Experimental Example 8); Through the animal experiments such as the effect on lung tissue changes (Experimental Example 9), it was confirmed that it exhibits excellent anti-inflammatory, anti-allergic and asthma-inhibiting activity, pharmaceutical composition for prevention or treatment of inflammation, allergy and asthma disease, health functional food Or it is useful as a dietary supplement.
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type http://data.epo.org/linked-data/def/patent/Publication

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