http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102093660-B1

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filingDate 2019-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1e6fae426a5f2ef1f1c78bc46e833c5
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publicationDate 2020-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102093660-B1
titleOfInvention Temperature-sensitive tissue adhesion prevention hydrogel composition and its manufacturing method
abstract The present invention relates to a hydrogel composition for preventing tissue adhesion and a method for manufacturing the same, more specifically, consisting of a polyethylene oxide-polypropylene oxide-polyethylene oxide ternary copolymer, water-insoluble hyaluronic acid, sodium alginate and purified water, Polyethylene oxide-polypropylene oxide-polyethylene oxide terpolymer having a molecular weight of 1 to 500 kDa is dissolved through heating at a temperature of 60 to 100 ° C. for 1 to 2 hours to dissolve the copolymer, and the solution prepared through the copolymer dissolving step Water-insoluble hyaluronic acid is mixed with the seafood, sodium alginate is mixed with the mixture prepared through the hyaluronic acid mixing step and the hyaluronic acid mixing step of stirring at a temperature of 10 to 20 ° C, and sodium is stirred at a temperature of 5 to 20 ° C. It is prepared through a manufacturing method consisting of an alginate mixing step. The hydrogel composition for preventing tissue adhesion and the manufacturing method comprising the above-described components and manufacturing method is based on a polyethylene oxide-polypropylene oxide-polyethylene oxide ternary copolymer having tissue adhesion inhibiting performance as a basic structure, and water-insoluble hyaluronic acid and sodium alginate. By blending to provide a hydrogel composition for preventing tissue adhesion that is evenly applied to the wound in the body.
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priorityDate 2019-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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