| abstract |
The present invention relates to a compact device for operatively coupling a solid planar substrate, such as a glass slide, to a microfluidic circuit and performing reactions or reactions to organic materials bound to the plane of the planar substrate. Typical reactions include binding, staining and / or labeling reactions. In use, a sealed reaction chamber is formed, the chamber containing at least a portion of the organic material and solid substrate. The headspace in a sealed chamber between solid substrates is generally of microfluidic dimensions, and diaphragm pump members are used to inject, exchange and / or mix fluids into the chamber. |