http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102088107-B1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-10
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filingDate 2018-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102088107-B1
titleOfInvention Inflammatory peptide-loadedinjectable hydrogel by physical or chemical loading, and method of manufacturing and application
abstract The present invention relates to a hydrogel as a carrier which can contain an inflammation inhibitory peptide in a physical or chemical manner and can deliver it, and a method for preparing the same. The hydrogel according to the present invention has a structure in which a peptide having an inflammatory inhibitory effect on a natural biomaterial is physically or chemically contained, and the peptide which is unstable in vivo is delivered to a disease site of an inflammatory response while having a stable and high biocompatibility. To be possible. Accordingly, it is possible to improve the low therapeutic efficiency due to the low bio stability of the inflammation inhibitory peptide, and to alleviate the side effects at the time of administration, which is shown by repeated administration. In addition, the pharmaceutical composition comprising the hydrogel according to the present invention can be applied to various formulations, such as injection formulations, it is possible to apply to the development of therapeutic agents for inflammatory diseases such as rheumatoid arthritis or degenerative joint disease.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20230042193-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210115502-A
priorityDate 2018-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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