http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102084227-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dcc9a9557481c4fd9739b6efbfa01db6 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0655 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
| filingDate | 2019-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cbea2511aa281bd92efba5fd1881306 |
| publicationDate | 2020-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102084227-B1 |
| titleOfInvention | Human transformed chondrocyte cell line mediated drug screening system for cartilage disease remedy |
| abstract | The present invention relates to a recombinant expression vector for screening a cartilage disease therapeutic agent, a cell line transformed with the expression vector, and a method for screening a drug effective for treating cartilage disease using the same. Since all constituent factors are composed of human-derived genetic factors, The new drugs selected through this study will be more effective in treating human cartilage disease. In addition, the present invention has the advantage of evaluating whether the cartilage disease treatment of genes that do not know the function through the additional transformation can be compared to the treatment function of cartilage disease of various drugs as well as the optimal treatment concentration and indirect cytotoxicity Evaluation is also expected. Finally, 2-anthraquinonecarboxylic acid, a novel substance having cartilage regeneration efficacy discovered through the screening system according to the present invention, is expected to be used for the treatment of various cartilage diseases. |
| priorityDate | 2018-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 358.