| abstract |
Methods of treating aging, or aging-related conditions, symptoms or diseases; How to stimulate hair growth, regeneration or pigmentation (or how to prevent hair loss); Methods of increasing the expression of adenosine receptors in dermal cells (with hair growth); Methods of treating a skin condition or disease, or one or more symptoms thereof, including cosmetic treatments (eg, wrinkles, hyperpigmentation, redness, injection, drying, gold, loss of firmness, loss of elasticity, skin thinning and loss of vitality) This is provided. The method comprises administering a sufficient amount of CBP / catenin (eg, CBP / β-catenin) antagonist as disclosed, in particular the administration of or above the symmetric division in the relevant somatic stem cell population. Sacrificially in an amount and manner sufficient to increase the number of asymmetric regenerative cleavage. In certain aspects, CBP / catenin (eg, CBP / β-catenin) antagonists include alkyl and / or fatty acid ester derivatives thereof disclosed herein. |