http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102055628-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_726e9d78ea4b7f6fd4a1c43d54daec0d |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0003 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 |
filingDate | 2019-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa97c8df8af8f81d0e5152d715420594 |
publicationDate | 2019-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102055628-B1 |
titleOfInvention | Method for producing heparin sodium using pig by-products |
abstract | The present invention relates to a method for producing heparin sodium using pig by-products, and more specifically, to a mixture prepared through the brine mixing step of mixing a brine having a mass concentration of 5 to 6% with a pig internal organ pulverized product. Acidity adjustment step of adjusting the pH of the mixture to 8 to 9 by adding sodium hydroxide, heating step of heating the mixture of which the acidity is adjusted through the acidity adjustment step, and standing the mixture heated by the heating step Separation step of separating the water, the cooling step of cooling the filtrate from which the water is removed through the water separation step, the heparin adsorption step of adsorbing heparin by contacting the filtrate cooled through the cooling step with a strong base anion exchange resin, the Heparin solution was prepared by immersing the strong base anion exchange resin to which heparin was adsorbed through the heparin adsorption step. Heparin solution manufacturing step, heparin solution prepared through the heparin solution manufacturing step by mixing ethanol and heparin sodium precipitation step of precipitation of heparin sodium and heparin sodium precipitated through the heparin sodium precipitation step to dry to dry step Is done. The method of manufacturing heparin sodium using pig by-products made through the above process does not need to be carried out by dividing the heating step in the process of adjusting pH, and the process of adding proteolytic enzymes is omitted so that heparin sodium of high purity is simplified by a simple process. Can provide. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102317445-B1 |
priorityDate | 2019-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.