http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102045870-B1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-306 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6842 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-28 |
filingDate | 2018-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102045870-B1 |
titleOfInvention | Novel amphiphiles with dendronic hydrophobic group and uses thereof |
abstract | The present invention relates to an amphiphilic compound having a dendritic hydrophobic group, a method for preparing the same, and a method for extracting, solubilizing, stabilizing or crystallizing a membrane protein using the same. When the compound according to the present invention is used, not only the membrane protein solubilization effect is excellent, but also the membrane protein can be stably stored in an aqueous solution for a long time, and thus can be utilized for its functional analysis and structural analysis. In particular, the amphiphilic compounds with dendritic hydrophobic groups showed excellent properties for visualization of protein complexes by electron microscopy. Membrane protein structure and function analysis is one of the areas of greatest interest in current biology and chemistry, and since more than half of currently developed drugs target membrane proteins, they are applied to the study of membrane protein structures closely related to drug development. This is possible. |
priorityDate | 2017-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 122.