http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102026675-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2561-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate | 2018-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-102026675-B1 |
titleOfInvention | Regulation mechanism of allergic reaction by miR-135a-5p and p62, and use thereof |
abstract | The present invention relates to an allergic response control mechanism and its use by miR-135a-5p and p62, specifically a method for measuring the expression level of p62 or miR-135a-5p in order to provide information necessary for the diagnosis of allergic diseases , a pharmaceutical composition for the prevention or treatment of allergic diseases containing miR-135a-5p or an agonist thereof as an active ingredient, and a screening agent for treating allergic diseases for treating a test compound in cells and measuring the expression level of miR-135a-5p or p62 It is about a method. According to the present invention, the method for measuring the expression level of p62 or miR-135a-5p can effectively provide information necessary for the diagnosis of allergic diseases, and the pharmaceutical composition according to the present invention containing miR-135a-5p or an agonist thereof. The composition can be used to effectively prevent or treat allergic diseases. In addition, the screening of substances that increase the expression of miR-135a-5p or decrease the expression of p62 can be effectively explored for the treatment of allergic diseases, which will greatly contribute to the development of new and more effective allergic diseases. It is expected. |
priorityDate | 2018-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 363.