http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102007919-B1

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filingDate 2017-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-102007919-B1
titleOfInvention Microfluidic chip and preparation method of free-standing porous membrane using the same
abstract The present invention relates to a microfluidic chip and a method for manufacturing a stand-alone porous membrane using the same, and more particularly, a first inlet through which a core liquid is injected, a flow separator for separating the injected core liquid into two or more flows, and a sheath liquid injected. An upper layer including a second inlet to be formed, a reaction channel portion to produce a multi-stranded microfiber by reacting the core liquid separated by the two or more streams, and a multi-stranded microfiber to be produced; ; An accumulation chamber connected to the outlet of the upper layer to accumulate the discharged multiple strands of fine fibers; And a filter provided in the accumulation chamber to filter the remaining sheath solution from the accumulated multi-stranded microfibers, wherein the core fluid and the sheath fluid are polar solutions, and the polarity of the core fluid is applied to the sheath fluid. In the method of manufacturing a stand-alone porous membrane using a microfluidic chip, the method comprises: (a) injecting a core fluid and a sheath solution into the first inlet and the second inlet, respectively, to prepare multi-stranded microfibers, and the scale chamber Accumulating in; And (b) repeating the immersion of the microfluidic chip having the accumulated multi-stranded microfibers in the sheath solution and forming a membrane two or more times to form a membrane. Through the above, simultaneously obtained microfibers of sub-micron-thick multi-stranded microfibers that could not be obtained by the conventional microfluidic spinning method, and using this to prepare a stand-alone porous membrane having micropores for drug delivery and tissue engineering It can be applied to tissue engineering fields such as a support.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7407842-B2
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priorityDate 2017-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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