http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102004902-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S514-924 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-04 |
| filingDate | 2017-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-102004902-B1 |
| titleOfInvention | Composition for tuberculosis comprising fusion protein |
| abstract | The present invention provides a polypeptide comprising at least one polypeptide selected from the group consisting of the polypeptide represented by SEQ ID NO: 1 and the polypeptide represented by SEQ ID NO: 2; And a fusion protein comprising ESAT-6 (6 kDa early secretory antigenic target) as an active ingredient. The present invention relates to, for example, a composition for tuberculosis vaccination. When the fusion protein provided by the present invention is used as an antigen, it exhibits a high IFN-gamma production ability in the spleen and lung of an animal model causing infection by Mycobacterium tuberculosis, increases the expression level of multifunctional CD4 + T cells, By maintaining the formation of acquired defense immunity and T-cell memory, it is possible to effectively prevent not only the active tuberculosis infection but also the reactivation of tuberculosis infection in latency period. |
| priorityDate | 2017-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 144.