http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101994805-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0066 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J13-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-30 |
| filingDate | 2012-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101994805-B1 |
| titleOfInvention | Process for the production of estetrol intermediates |
| abstract | (A) reacting a compound of formula (II) with an acylating agent or silylating agent to form a compound of formula (III): < EMI ID = Wherein P 1 and P 2 are each independently a protecting group selected from R 2 -Si-R 3 R 4 , or R 1 CO-, wherein R 1 is a group wherein each group is independently fluorine or C 1 - is optionally substituted with one or more substituents selected from 4 alkyl, C 1 - 6 alkyl or C 3 - 6 cycloalkyl; R 2, R 3 and R 4 are each, each group is independently a fluorine or a C 1 - 4 optionally substituted by one or more substituents selected from alkyl, C 1 - 6 alkyl or phenyl; b) reacting a compound of formula (III) in the presence of palladium acetate or a derivative thereof to prepare a compound of formula (IV); c) reacting the compound of formula (IV) with a reducing agent to produce a compound of formula (I). |
| priorityDate | 2011-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 118.