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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6812
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B15-00
filingDate 2016-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101975639-B1
titleOfInvention Methods for Predicting a Potential for Protein Aggregation
abstract The present invention relates to a method for predicting protein aggregation potential and an analytical method for determining the risk of amyloid fibril hyperdisease. The present invention is based on the cis-trans isomerization of proteins, in particular β-2-microglobulin, and the structural and thermodynamic changes therefrom as a measure of reliable information for predicting the folding and aggregation of proteins, in particular β-2-microglobulin Can be provided. Accordingly, the present invention can be usefully used in the development of drugs that treat or prevent various protein conformational disorders and in the formulation of strategies for designing cohesion-resistant proteins as biological therapeutic agents.
priorityDate 2016-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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