http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101975639-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-50 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B15-00 |
filingDate | 2016-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101975639-B1 |
titleOfInvention | Methods for Predicting a Potential for Protein Aggregation |
abstract | The present invention relates to a method for predicting protein aggregation potential and an analytical method for determining the risk of amyloid fibril hyperdisease. The present invention is based on the cis-trans isomerization of proteins, in particular β-2-microglobulin, and the structural and thermodynamic changes therefrom as a measure of reliable information for predicting the folding and aggregation of proteins, in particular β-2-microglobulin Can be provided. Accordingly, the present invention can be usefully used in the development of drugs that treat or prevent various protein conformational disorders and in the formulation of strategies for designing cohesion-resistant proteins as biological therapeutic agents. |
priorityDate | 2016-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.