http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101973079-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55544 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0258 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-245 |
| filingDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101973079-B1 |
| titleOfInvention | Antigen chimera, antigen combination, vaccine, method of preparing same, and kit thereof |
| abstract | The present invention relates to a fusion protein comprising a mucosal adjuvant protein monomer capable of forming an antigen and a multimer; And a mucosal adjuvant protein monomer capable of forming the multimer, wherein the mucosal adjuvant protein monomer capable of forming the multimer comprises cholera toxin B subunit (CTB) and E. coli heat mutant Wherein the molar ratio of the fusion protein to the mucosal adjuvant protein monomer capable of forming the multimer is 1: 1 or less, and the molar ratio of the fusion protein to the mucosal adjuvant protein monomer in the chimeric antigen is 1: 4. In the present invention, in order to produce more potent antigens, a chimeric construct is prepared using the property that a mucosal adjuvant protein can form a pentamer. In addition, in order to improve the immunogenicity enhancing effect of the antigen, the mucosal adjuvant protein is used to improve the immune effect. In addition, the chimeric protein antigen formed together with the recombinant antigen of the present invention stimulates the mucosa to produce secretory IgA and induce mucosal immunity. |
| priorityDate | 2013-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.