| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0272d70c9ba3abebfdf08dc6b96f1120 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G81-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M37-0015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G18-4018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-30 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G18-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 |
| filingDate |
2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_beb60e575ce6ee186bacaa422932a72c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_125a3eb678029ec2867cf954d2da23dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e674e2eeb142b815a4b38100fc955f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48f7e6e3b49f40e8b54728703211b2ed |
| publicationDate |
2019-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-101964526-B1 |
| titleOfInvention |
pH sensitive block copolymer, and injectable formulation for DNA vaccine using thereof |
| abstract |
The block copolymer for pH-sensitive micelles according to one aspect of the present invention has a repeating unit represented by the general formula (3), which is prepared from oligomer sulfamethazine (OSM), polyethylene glycol (PEG), and polyamino ester urethane (PAEU) . According to another aspect of the present invention, an injection preparation for DNA vaccine may be a multi-block coating of a component comprising the block copolymer for pH-sensitive micelles and a DNA vaccine on a multi-micro needle. The block copolymer for pH-sensitive micelles according to the present invention and the injectable composition for DNA vaccines using the same are characterized in that a component including a pH-sensitive block copolymer and a DNA vaccine, which are charged to an anion or a cation in a specific pH region, Thus, the delivery efficiency of the DNA vaccine is not deteriorated and the injection pain is not caused by the multi-micro needle. In addition, the injectable DNA vaccine according to the present invention has an advantage of increasing the distribution stability and storage stability of a DNA vaccine in a dry state without a cold chain by formulating a DNA vaccine into a micro needle. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113633613-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113633613-A |
| priorityDate |
2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |