http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101956771-B1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2527-143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2563-107 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B32-194 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B32-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2016-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101956771-B1 |
titleOfInvention | Graphene nano sensor for detecting target rna |
abstract | The present invention relates to a graphene nanosensor for detecting target RNA, which is capable of pegylating a target nucleic acid to a fluorescent dye-labeled PNA (peptide nucleic acid) aptamer, sequence of graphene nanoparticles prepared by contacting graphene nanoparticles with grafts attached thereto, it is possible to replace the existing FISH analysis, and thus can be applied to various fields of basic biology, and can be applied to a disease-specifically overexpressed RNA biomarker and It can detect RNA biomarkers at low cost and can easily and quickly identify the specific RNA expression and distribution of interest in the entire embryonic tissue during the development process. In addition, siRNA treatment can easily detect the inhibitory effect of target mRNA, and RNA can be detected in living tissues, It is possible to trace changes, to obtain high reliability and resolution results, to detect multiple target RNAs simultaneously, and to simultaneously detect various RNAs present in one cell. In clinical applications, It can be used for all diseases that can be confirmed by tissue or cell, and it can be used for diagnosis of diseases, details and progress, can select patient-customized drugs, can diagnose fast diseases, Lt; RTI ID = 0.0 > RNA < / RTI > for detection of target RNA. The present invention can detect target RNA with high sensitivity at a rapid, simple and low cost in tissue section inspection, and thus can exert an excellent effect in clinical use and can replace FISH. |
priorityDate | 2016-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.