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filingDate 2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101956450-B1
titleOfInvention Nanoparticle complexes for specific delivery of RNA and preparation method thereof
abstract The present invention relates to a nanoparticle complex for RNA-specific transfer and a method for producing the same. Nanoparticle composites comprising a gold nanoparticle and a cationic polymer adhered as a surface modifying substance on the surface of gold nanoparticles were prepared using the RNA specific transfer nanoparticle complex according to the present invention and a method for producing the same , Can be used to deliver siRNA structural transduction liRNA or tiRNA to cells to cause RNA interference. In addition, by utilizing the superior gene silencing effect of the liRNA or tiRNA-specific transferring nanoparticle complex having improved structure and functional characteristics, it can be utilized for a next-generation disease treatment based on RNA interference.
priorityDate 2016-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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