Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 |
filingDate |
2016-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2019-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-101956302-B1 |
titleOfInvention |
intracellular pH-responsive fusion peptide, phamaceutical composition for treatment of protein aggregation and misfolding related diseases |
abstract |
The pH-sensitive fusion peptide according to the present invention has a structural change due to a change in pH due to a positively-charged cell permeable peptide comprising arginine residues containing 2 to 15 arginine residues and a beta-sheet-forming fragment. Due to this structural change, it is possible to control the antipruritic activity and cytotoxic ability of the fusion peptide so that it can be used at the proper site. |
priorityDate |
2016-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |