| abstract |
The present invention relates to therapeutic compositions and / or formulations comprising at least one crosslinking protein matrix comprising at least one protein residue and at least one saccharide-containing moiety, and to a process for its preparation. The cross-linking protein matrix may be prepared by reacting full length or substantial full-length proteins such as tropoelastin, elastin, albumin, collagen, collagen monomers, immunoglobulins, insulin and / or derivatives or combinations thereof with a saccharide- , Cross-linking with a polysaccharide crosslinking agent derived from hyaluronic acid or a cellulose derivative. The therapeutic composition may be administered topically or by injection. The present disclosure also provides methods, systems and / or kits for the manufacture and / or formulation of the compositions disclosed herein. |