abstract |
The present invention provides polypeptides comprising a complement factor B analog. The present invention also provides a variety of complement Factor B analogs and related methods, nucleic acids and vectors containing a complement Factor B analog comprising a mutation of the free cysteine amino acid. These complement factor B analogs and related methods, nucleic acids and vectors may be used to modulate the complement pathway or to study and / or treat a variety of diseases or disorders related to the complement pathway. |