http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101947141-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2405-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-04012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-285 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-916 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2878 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-04012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2016-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101947141-B1 |
| titleOfInvention | Composition and method for detecting a diagnostic marker for amyotrophic lateral sclerosis using acid sphingomyelinase |
| abstract | The present invention relates to a composition for diagnosing amyotrophic lateral sclerosis (ALS) using acid sphingomyelinase (ASM) and a diagnostic marker detecting method, and more particularly, (b) measuring the expression level or enzyme activity level of ASM in the sample; And (c) determining that the expression level or enzymatic activity level of the ASM is increased compared to a normal person and that the increased body of the ASM is ALS-stained. The present inventors have found that the activity of ASM among lipids and enzymes involved in sphingolipid metabolism is specifically increased in ALS patients as compared with normal subjects. This can be used as a marker for diagnosing ALS, thereby developing new and effective diagnostic reagents. |
| priorityDate | 2016-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 164.