Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10041 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8613 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-65 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
filingDate |
2012-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2019-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-101946666-B1 |
titleOfInvention |
Conditionally replication-competent adenovirus |
abstract |
The present invention aims to provide a novel limited proliferation-type adenovirus and a reagent for the detection of cancer cells containing the same or a diagnostic reagent for cancer. The present invention also encompasses a polynucleotide comprising a human telomerase reverse transcriptase (hTERT) promoter, an E1A gene, an IRES sequence and an E1B gene in this order and also comprising a target sequence of a first miRNA. Wherein the cloning cassette comprising the polynucleotide is inserted into the E1 region of the adenoviral genome. |
priorityDate |
2011-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |