| abstract |
The present invention relates to a thioaryl derivative of the following formula (1), a process for its preparation, a pharmaceutical composition containing the same, and a use thereof, wherein the thioaryl derivative according to the present invention promotes GLP-1 production in the gastrointestinal tract as a GPR120 agonist And can be used for the prevention and treatment of diabetes, complications of diabetes, inflammation, obesity, non-alcoholic fatty liver, fatty liver or osteoporosis by improving insulin resistance by anti-inflammatory action in macrophages and pancreatic cells. [Chemical Formula 1] Wherein A, B, D, E, F, G, H, I, J, K, M, R1, R2, R3, R4, R5, R6, R7 and n are as defined in the specification. |