| abstract |
(I) as a nucleoside assembly inhibitor for the treatment of viruses, including, but not limited to, pregenomic RNA encapsidation inhibitors of HBV for hepatitis B (HBV) ) And novel methods of using these compounds. R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 are independently selected from the group consisting of hydrates, solvates, pharmaceutically acceptable salts, prodrugs, Lt; / RTI > are as defined herein. |