http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101924947-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S514-909 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S514-866 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4741 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4741 |
| filingDate | 2017-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101924947-B1 |
| titleOfInvention | Isoquinolinoquinazolinones as therapeutic drugs or composites for obesity and metabolic diseases |
| abstract | The present invention relates to a compound for the treatment of isoquinolinoquinazoline obesity and metabolic diseases, and more particularly, to a compound for treating obesity and metabolic disease by using isoquinolinoquinazoline substance antagonizing PPAR gamma, a nuclear receptor, A substance strongly inhibiting transcriptional activity and a method for producing the same. The present invention provides a compound represented by the general formula (1) wherein R¹, R² and R³ are hydrogen, a methyl group or a methoxy group, and R⁴ and R 5 represent hydrogen, chlorine Y is a carbonyl group, and X is an immune group. The compounds according to the present invention are less toxic than conventional antagonists and have an inhibitory effect on adipocyte differentiation up to 80%, which is effective in treating obesity and metabolic diseases. |
| priorityDate | 2017-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 342.