http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101916567-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0619 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M41-46 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0793 |
| filingDate | 2017-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101916567-B1 |
| titleOfInvention | Intervertebral disc cell co-culture device for the study of intervertebral disc pain control mechanism |
| abstract | The microcurrent stimulating disc cell co-culture apparatus for studying the intervertebral disc space mechanism according to an embodiment of the present invention includes: an intervertebral disc chamber in which inflammation-treated intervertebral disc cells are cultured; Neural chambers in which neurons are cultured; A connection channel connecting the nerve chamber and the disc chamber; An electrical stimulation part installed in the nerve chamber for providing electrical stimulation to the nerve cell; A piping connecting the inlet of the nerve chamber and the outlet of the intervertebral disc chamber; A circulation part installed in the piping, wherein the pain inducing substance expressed in the nerve cell flows from the nerve chamber to the intervertebral disc chamber and is operated so that the nerve stimulating substance in the intervertebral disc chamber flows into the outlet port; And a medium supply member connected to the injection port by piping to continuously supply the culture medium to the injection port during operation of the circulation unit so as to suppress the oxidation-reduction reaction of the culture medium at the injection port, wherein the inflammation-treated intervertebral disc cells and nerve cells Independently cultured, the nerve stimulating substance secreted from the inflammation-treated intervertebral disc is introduced into the nerve chamber through the connecting channel to stimulate the nerve cell, and the pain-causing substance secreted from the nerve cell by the stimulation of the nerve stimulating substance, It is preferable to observe whether the disc herniation is stimulated by stimulating the intervertebral disc cells and whether the amount of pain inducing substance is suppressed when the stimulation is applied to the nerve cell. |
| priorityDate | 2017-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 280.