abstract |
There is provided an intact human antibody or an antigen-binding fragment of a human antibody that specifically binds to and inhibits human TNF-like ligand 1A (hTL1A). The human anti-hTL1 A antibody may be used for the treatment of inflammatory diseases or diseases such as inflammatory bowel disease including ulcerative colitis and Crohn's disease, rheumatoid arthritis and the like; Autoimmune diseases or diseases such as multiple sclerosis, diabetes mellitus and the like; And allergic reactions such as asthma and allergic pulmonary inflammation. |