http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101894769-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab3413f8184feb74be59b7ed962a5b97 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate | 2018-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4563e26caa83eb7bcd6ad9610ad05a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5d71ef86e68deea5d8d6216a2d96d01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e418551b517340e9db3a1c4aee25dc5f |
| publicationDate | 2018-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101894769-B1 |
| titleOfInvention | Composition Comprising Short Interfering RNAs for Preventing or Treating Neurofibrosarcoma |
| abstract | The present invention relates to a composition for preventing, ameliorating or treating neurofibromatosis malignant tumor comprising TNS3 gene expression-inhibiting siRNA (short interfering RNA) as an active ingredient. According to the present invention, the siRNA is a tumor in showed an over-expression (overexpression) are effective suppressors bar, cell experiments and TNS3 gene expression control siRNA in animal experiments confirmed that this is a good effect on growth inhibition and treatment of malignant tumor by inhibiting the expression of TNS3 gene, also TNS3 The siRNA composition has an excellent effect in inhibiting the growth and treatment of type 1 neurofibromatosis malignant tumors, particularly when used in combination with ICE (iopospermide, carboplatin, etoposide) anticancer agents. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019112242-A1 |
| priorityDate | 2017-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 123.