http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101889434-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20480c34cdf10fe8566594f4d9551fd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b76c1d7f523cf99928eb2f2a602ea743 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-28 |
filingDate | 2017-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bff61238d885c0e2666d11bf9376dbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d48bdda34ba1a349f2dad5e24671db93 |
publicationDate | 2018-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101889434-B1 |
titleOfInvention | Pharmaceutical composition for prevention or treatment of anti-thrombosis comprising black burdock root extracts as an effective component and health functional food comprising the effective component |
abstract | The present invention relates to a method for producing The present invention relates to a pharmaceutical composition and a health functional food for preventing or treating thrombosis, which comprises a black burdock extract prepared by heat-treating a ground portion in a sealed container at a high temperature under a high temperature condition as an active ingredient. More particularly, The burdock root was heated in a sealed container at 70 ~ 80 ℃ for 10 days or more and then aged at low temperature for 1 ~ 2 days. The hot water or ethanol extract of black burdock was prepared and fractionated with ethyl acetate The present invention relates to a pharmaceutical composition and a health functional food for preventing or treating / improving thrombosis through inhibition of blood clotting, which comprises a fraction as an active ingredient. The pharmaceutical composition for the prevention or treatment of thrombosis according to the present invention and the black burdock extract as an active ingredient of the health functional food can be obtained by inhibiting thrombogenesis-related enzymes and inhibiting blood coagulation factors Exhibits a strong antithrombotic activity, exhibits no hemolytic activity on human erythrocytes, exhibits excellent thermal stability, and does not show loss of the thrombogenesis-related enzymes and blood coagulation factor inhibitory effects in an acidic condition of pH 2 and in plasma Since the antithrombotic component can be recovered more than 16 times as compared to burdock, it is expected that it can be used for prevention and treatment of thrombosis such as ischemic stroke and hemorrhagic stroke through improvement of blood circulation, It can be prepared in various forms such as ring, tablet, etc., It is a very useful invention in the pharmaceutical industry and food industry because of its excellent effect. |
priorityDate | 2017-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 133.