abstract |
The present invention provides methods and pharmaceutical compositions for preventing or treating alopecia, for example, chemotherapy-induced alopecia (CIA). The pharmaceutical compositions of the present invention include vitamin D compounds as effective doses of vitamin D compounds in formulations that deliver the vitamin D compound locally to the epidermal layer but are substantially prevented from being delivered to the dermal layer. In chemotherapy patients, the pharmaceutical compositions of the invention may be administered prior to, or concurrently with, chemotherapeutic drug administration. |