Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 |
filingDate |
2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2018-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-101879926-B1 |
titleOfInvention |
Mrna-based gene expression for personalizing patient cancer therapy with an mdm2 antagonist |
abstract |
This invention discloses a method for predicting the responsiveness of a cancer patient to treatment with an MDM2 antagonist of the formula I, II and III as disclosed herein, said method comprising administering at least MDM2 as a biomarker for predicting the response, Includes measuring mRNA expression levels of four gene panels including MDM2, XPC, BBC3 and CDKN2A. |
priorityDate |
2013-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |