http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101864234-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44f04d319aaa6e66f240244bc905f452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_83dffc287358331deccd774ddf93f551 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-10 |
| filingDate | 2017-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfefd4848fea6879e87aa1eb877b154a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e15ebf9f7abaf648ab26c41d46bcb32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a56e363473341308171b72d4dcc4c23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b2e31a9694945f54213a65d2c943237 |
| publicationDate | 2018-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101864234-B1 |
| titleOfInvention | Composition for preventing, improving or treating erectile dysfunction comprising cavernous derived exosome |
| abstract | The present invention relates to a composition for preventing or treating erectile dysfunction, comprising corpus cavernosum penis-derived exosomes as an effective component, wherein the composition includes a pharmaceutical composition, a quasi-drug composition, a functional health food, and the like. The corpus cavernosum penis-derived exosomes of the present invention, and in particular, exosomes derived from the pericyte cells of corpus cavernosum penis increase the expression of platelet endothelial cell adhesion molecule-1 (PECAM-1) which is a vascular endothelial cell-specific protein, neural/glial antigen 2 (NG2) which is a pericyte cell-specific protein, alpha-smooth muscle actin (α-SMA) which is a smooth muscle cell-specific protein, and beta-III tubulin which is a neuron-specific protein, and improves the tube formation ability of endothelial cells in the corpus cavernosum penis. Unlike conventional erectile dysfunction drugs that attempt to improve erectile dysfunction through a transient increase in the blood flow, the corpus cavernosum penis-derived exosomes of the present invention fundamentally address an abnormalized structure of corpus cavernosum penis, and thus provide therapeutic effects for erectile dysfunction. Accordingly, the corpus cavernosum penis-derived exosomes of the present invention may be widely used in the biomedical field related to erectile dysfunction. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114507642-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200018845-A |
| priorityDate | 2017-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.