abstract |
A method of making a hydrogel for an intra-articular supplement, - providing an alginate solution, Providing a solution having chitosan having an Mw of less than 60 kD, Mixing the alginate solution and the chitosan solution, wherein the mixed solution comprises 0.5 to 0.7% (w / v) chitosan and 1 to 1.4% (w / v) - introducing the droplets of the mixed solution into a solution having Ca 2+ or Sr 2+ cations and - separating the polymerized beads from the solution having the cation ≪ / RTI > a method for preparing a hydrogel for an intra-articular supplement. |