| abstract |
The present invention provides pyridone and aza-pyridone compounds (including stereoisomers, tautomeric pharmaceutically acceptable salts thereof) of Formula I useful for the inhibition of Btk kinase and for the treatment of immune disorders, such as inflammation mediated by Btk kinase, . Methods for the use of compounds of formula I for in vitro, in vitro and in vivo diagnosis and treatment of such disorders or associated pathological conditions in mammalian cells are disclosed. (I) |