abstract |
a novel heterocyclic compound or a salt thereof useful for selectively inhibiting the degradation of p27 Kip1 . This compound or its salt is represented by the following formula (1). [Wherein A represents an alkyl group, a cycloalkyl group, an aryl group, or a heterocyclic group, the group A may have a substituent; Ring B represents a 5- to 8-atom monocyclic heterocyclic ring or a condensed ring containing the monocyclic heterocyclic ring, ring B may have a substituent; Ring C represents an aromatic ring, ring C may have a substituent; L represents a linker in which the main chain has 3 to 5 atoms selected from a carbon atom, a nitrogen atom, an oxygen atom and a sulfur atom, and also has at least one hetero atom selected from a nitrogen atom, an oxygen atom and a sulfur atom, L may have a substituent; n is 0 or 1; |